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Community-informed connectomics of cortical intrinsic organization in participants with subjective cognitive decline
Qian Chen1, Jilei Zhang2, and Bing Zhang1
1Department of Radiology, Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China, 2Philips Healthcare, Shanghai, China
Individuals with subjective cognitive decline showed disruptions in the cortical intrinsic organization of visual and dorsal attention networks and enhanced intra-module interaction of the frontoparietal network.
Figure 2. A Distribution of cortical within-module degree (WMD) and participation coefficient (PC) averaged across 32 normal controls (NC). B Differences between NC (gray) and 36 participants with subjective cognitive decline (SCD) (black). Scatterplots represent WMD/PC values in significant clusters. Findings were adjusted for age, gender, and years of education.
Figure 1. Gordon’s 333 cortical parcels and 10 predefined communities. AN: auditory network; DMN: default mode network; FPN: frontoparietal network; SN: salience network; VN: visual network; CON: cingulo-opercular network; DAN: dorsal attention network; MTN: medial temporal network; SMN: sensorimotor network; VAN: ventral attention network.