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Oxytocin function regulation in autism spectrum disorders probed with rsfMRI complexity analysis
Kaundinya Gopinath1, Elissar Andari1, and Larry Young1
1Emory University, Atlanta, GA, United States
ASD patients exhibited increased fMRI signal complexity (i.e., synaptic noise) in a number of brain function networks. Oxytocin administration helped attenuate synaptic noise in these cognitive networks
Table 1: Significant (FDR q < 0.05) ASD vs Healthy Controls t-tests for different SEs.
Figure 1: FMRI signal complexity (SE) in social cognition RSN in ASD subjects decreases with increased DNA methylation levels in their OXTR gene CpG16 site