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5-Minute MR Fingerprinting from Acquisition to Reconstruction for Whole-Brain Coverage with Isotropic Submillimeter Resolution
Yilin Liu1, Yong Chen2, and Pew-thian Yap1
1University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 2Case Western Reserve University, Cleveland, OH, United States
We develop a 3D MRF sequence coupled with a novel end-to-end deep learning image reconstruction framework for rapid and simultaneous whole-brain quantification of T1 and T2 relaxation times with isotropic submillimeter spatial resolution. 
Fig 1. (A) The original MRF framework. (B) Our approach.
Fig 2. Low-resolution (left) and high-resolution (right) T1 and T2 maps of the same subject.