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Preoperative cerebral small vessel disease is independently associated with cerebral hyperperfusion after carotid endarterectomy
Xiaoyuan Fan1, Zhichao Lai1, Tianye Lin1, Juan Wei2, and Feng Feng1
1Peking Union Medical College Hospital, Beijing, China, 2GE Healthcare, Beijing, China
This study demonstrated that preoperative WMHs, lacunes, total cerebral SVD score, and carotid near-occlusion were independently associated with CH after CEA. In patients diagnosed with CH based on CBF imaging, patients who developed CHS had a higher systolic BP in the early postoperative period compared with those who did not.
Table 2. Logistic regression analysis of risk factors for postoperative cerebral hyperperfusion.
Receiver operating characteristic (ROC) curves of the preoperative Fazekas score for white matter hyperintensities (WMHs) (A) and the number of lacunes (B) for prediction of cerebral hyperperfusion (CH) after surgery. (C) ROC curves of preoperative radiological markers (Fazekas score of WMHs and the number of lacunes combined with the presence of carotid near-occlusion) for prediction of CH after surgery. (D) Relationships between the Fazekas score of WMHs, the number of lacunes, carotid near-occlusion, and postoperative CH.