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Alternations of functional networks in adult PTSD: a systematic review and meta-analysis of resting-state functional connectivity studies
WeiJie Bao1, YingXue Gao1, Hailong Li1, jing Liu1, Lingxiao Cao1, Xuan Bu1, and Xiaoqi Huang1
1Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Our findings suggested that the long-lasting effect of trauma on the function of the default mode network (DMN) and limbic network (LN) regardless of whether it caused symptoms of PTSD.
Figure 3. Brain networks dysfunction patterns of posttraumatic stress disorder. DMN, default mode network; VAN, ventral attention network; DAN, dorsal attention network; SMN, somatomotor network; LN, limbic network; FPN, frontoparietal network
Figure 2. The results of the meta-analysis of altered resting-state functional connectivity with the default mode network (DMN) and limbic network in the PTSD group compared with the groups of trauma-exposed controls (TEC) or nonexposed controls (NEC).