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Correlations between microstructural changes of anterior cingulum cortex and cerebral small vascular disease induced depression : A DKI Study
Zhenyu Pan1, Kun li1, Dongtao Liu2, Xiuqin Jia1, Qiao Bu1, Rui Jia1, Tao Jiang1, Yueluan Jiang3, Qinglei Shi3, and Lichun Zhou2
1Department of Radiology, Beijing Chao-Yang Hospital, Beijing, China, 2Department of Neurology, Beijing Chao-Yang Hospital, Beijing, China, 3MR Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China
The study aimed to find the correlation between microstructural changes of ACC and CSVD-induced depression patients by DKI. The results showed DKI parameters of ACC are potentially useful for the quantitative evaluation the degree of CSVD-induced depression.

Figure 2. Images of CVSD-D patient (A-1, T1WI 3D MPRAGE, A-2, DKI-Dmean map) and CVSD-ND patient (B-1, T1WI 3D MPRAGE, B-2, DKI-Dmean map). Compared with non-depression CVDS patient, the Dmean map of CVSD-D patient have more warm pixels in region of ACC. White arrow indicate left ACC.

Table 1. A comparison of DKI derived parameters in ACC between two groups.

Note: Values are presented as mean ± SD or median (interquartile range). Abbreviations: Dmean, mean diffusivity; KFA, kurtosis fractional anisotropy; Kmean, mean kurtosis.