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Altered global functional network connectivity and its relationship to cognitive dysfunction in rheumatoid arthritis
Zeyu Liu1, Bo Hou1, and Feng Feng1
1Peking Union Medical College Hospital, Beijing, China
This study demonstrated the altered FCS in RA patients using rs-fMRI. The decreased FCS was correlated to worsening performance in MMSE and MoCA. The increased FCS of the left inferior parietal lobule/supramarginal gyrus in RA may partially compensate for cognitive dysfunction in RA.
The images show the mean FCS in RA (A), HC (B) and the difference between RA and HC (C). The color bar at the bottom of each picture represents the FCS value for each group.
The correlation between FCS and neuropsychological scores (A, MMSE; B, MoCA) in RA patients. The color bar represents the ! value.