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Simultaneous quantification of T2 and T2* by accelerated 10-echo GESE-EPIK sequence for carrageenan-phantoms and in vivo data
Fabian Küppers1,2,3, Seong Dae Yun1, and N. Jon Shah1,2,4,5
1Institute of Medicine and Neuroscience 4, Forschungszentrum Juelich GmbH, Jülich, Germany, 2Institute of Medicine and Neuroscience 11, Forschungszentrum Juelich GmbH, Jülich, Germany, 3RWTH Aachen University, Aachen, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Germany, 5JARA - BRAIN - Translational Medicine, Aachen, Germany
Simultaneous quantification of T2 and T2* within 1 minute using improved 10-echo GESE-EPIK is validated for phantoms and in vivo with reference methods. Successful WM/GM separation is shown. Sequence acceleration is investigated with (t)SNR analysis.
Figure 4: In vivo relaxation quantification results. One exemplary slice for T2 and T2* maps from GESE-EPIK and the reference methods is shown in the top left corner. T2* and T2 histograms from all acquired slices compare each parameter distribution from GESE-EPIK with its reference method. Mean values of each distribution with its standard deviation are given.
Figure 2: Reconstructed images from 10-echo GESE-EPIK for four exemplary slices of an in vivo data set. The TE for each echo is given. The signal strength of later echoes is modulated for visualisation purposes.