1826
Highly accelerated compressed sensing chemical exchange saturation transfer
Ying-Hua Chu1, Patrick Alexander Liebig2, He Wang3, and Yi-Cheng Hsu1
1MR Collaboration, Siemens Healthcare Ltd., Shanghai, China, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China
Compressed sensing can accelerate CEST imaging using SPACE acquisition. With two shots, the APTw images had only 0.5% error compared with the full acquisition with two averages. The whole-brain acquisition for one RF offset was reduced to 6 seconds with compressed sensing acquisition.
Figure2: The APTw images of brain and phantom acquired by Full sampled 13 shots, CS 3 shots, CS 2 shots and CS 1 shots. CS 3 shots and CS 2 shots have similar APTw images as the full sampled one, but for CS 1 shot, some sharp boundaries were smeared or distorted.
Figure1: The k-space sampling pattern for 3, 2, and 1 shot compressed sensing acquisition.