Sultan Zaman Mahmud1,2, Thomas S. Denney1,2, and Adil Bashir1,2
1Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, 2Auburn University MRI Research Center, Auburn University, Auburn, AL, United States
1Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, 2Auburn University MRI Research Center, Auburn University, Auburn, AL, United States
Blood-brain barrier (BBB) plays very important role in protecting the brain tissue and regulates the exchange of water from intra to extravascular space. This study demonstrates the reproducibility and validation of a non-invasive technique to assess the BBB using the MT effect on ASL signal.
Figure 1:
Perfusion (a), water extraction fraction (b), permeability surface area product
(c) and magnetization transfer ratio (d) maps from one control subject.
Figure 2: Bland-Altman
plots for test-retest results for perfusion (a) and water extraction fraction
(b). Correlation plots for test-retest results for perfusion (c) and extraction
fraction (d).
