2026
Probing human cortical microstructure using diffusion MRI: Insights from N=17,646 individuals of the UK Biobank.
Ivan Maximov1,2, Dennis van der Meer2, Ann-Marie de Lange2, Tobias Kaufmann2, and Lars T. Westlye2
1Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway, 2NORMENT, University of Oslo, Oslo, Norway

Diffusion MRI measure on the cortex
Brain age prediction using diffusion MRI in grey matter

Diffusion UK Biobank data for 17,646 subjects in grey matter

Figure 2 Mapping of the mean diffusion metrics over 17,646 subjects on the cortex: fractional anisotropy (FA), mean kurtosis (MK), and axonal water fraction (intra) from SMT MC model.
Figure 4. Brain age predictions using FA, MK, and SMT MC intra diffusion metrics estimated over Desikan-Killiany atlas of cerebral cortex. The predicted brain age values have been corrected for age bias. The predictions were estimated using XGBoost algorithm for linear model with sex and scanner site variables as covariance.