Joao Filipe Fernandes1, Harminder Gill1, Julio Sotelo2,3,4, Shu Wang1, Alessandro Faraci1, Cristian Montalba5, Jesus Urbina6, Ronak Rajani1, David A. Nordsletten1,7, Kawal Rhode1, Sergio Uribe6,8,9, and Pablo Lamata1
1School of Biomedical Engineering and Imaging Sciences, King’s College, London, United Kingdom, 2School of Biomedical Engineering, Universidad de Valparaiso, Valparaiso, Chile, 3Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Millennium Nucleus for Cardiovascular Magnetic Resonance, ANID - Millennium Science Initiative Program, Santiago, Chile, 5Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 6Radiology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile, 7Departments Biomedical Engineering and Cardiac Surgery University of Michigan, Ann Arbor, MI, United States, 8Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 9Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile
1School of Biomedical Engineering and Imaging Sciences, King’s College, London, United Kingdom, 2School of Biomedical Engineering, Universidad de Valparaiso, Valparaiso, Chile, 3Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Millennium Nucleus for Cardiovascular Magnetic Resonance, ANID - Millennium Science Initiative Program, Santiago, Chile, 5Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 6Radiology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile, 7Departments Biomedical Engineering and Cardiac Surgery University of Michigan, Ann Arbor, MI, United States, 8Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 9Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile
The study provides a 4D-flow-MRI in-vitro way to assess tailored compliant 3D-printed aortic valves.The results offer further proof that no-invasive pressure drop (∆P) based on full velocity profileovercomes the maximal velocity ∆P used clinically.
Experiments results of transvalvular
pressure drop (ΔP) measured invasively via peak-to-peak and
non-invasively via simplified advective work-energy relative pressure
(SAW) and simplified Bernoulli (SB). CO1, CO2 and CO3 represent
respectively the pulsatile with a maximal flow rate of 150ml/s, 200ml/s
and 250ml/s.
Phantom set-up representation, with the illustration where the valves were implemented.
