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Comparison of MRI and CT for Prediction of Microvascular Invasion in Solitary Hepatocellular Carcinoma: Which Imaging Modality Is Better?
Xiang-Pan Meng1, Yuan-Cheng Wang1, and Shenghong Ju1
1Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China
 CT and MRI had comparable predictive performance for MVI in solitary HCC. Only the radiomics signature at MRI had significant added value for MVI prediction on HCC > 2 and ≤ 5 cm.
(a) Schematic of two-trait predictor of venous invasion (TTPVI), arterial peritumoral enhancement, non-smooth tumor margin, and capsule appearance. (b) Frequencies of presence and absence of the four features at CT and MRI. The number of cases showing TTPVI, arterial peritumoral enhancement, non-smooth tumor margin and capsule appearance at MRI but not at CT was 15, 12, 7, 18, respectively; Number of cases presenting the four features at CT but not at MRI were 5, 3, 6, and 0, respectively. (c) Sensitivity and specificity of the four features for MVI diagnosis at CT or MRI.
Odds ratios of each variable contributing to the R and RR models at CT or MRI. R model = Radiographic model; RR model = radiographic-radiomics model; RS = radiomics signature; TTPVI = two-trait predictor of venous invasion.