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Microvascular Invasion has no Independent Effect on Recurrence in Small Hepatocellular Carcinoma: A Propensity Score Matching Analysis
Huan-Huan Chong1,2, Pei-Yun Zhou3,4, Chun Yang2, and Meng-Su Zeng1,2,5
1Shanghai Institute of Medical Imaging, Shanghai, China, 2Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, 3Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China, 4Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China, 5Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai, China
Although MVI independently impaired RFS before balancing the confounder — tumor size, it was ultimately identified as a potential but not an independent risk factor for recurrence in sHCC patients after PSM.
Figure 1. Flowchart of the study population. (a) the workflow of our study population before and after propensity score matching (PSM); (b) the frequency of MVI stratified by tumor size.
Figure 2. The Kaplan-Meier curves in terms of MVI statuses and grades. (a) and (b) were stratified by MVI statuses and grades in the Pre-PSM subgroup, respectively; (c) and (d) were stratified by MVI statuses and grades in the Post-PSM subgroup , respectively.