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Staging chronic hepatitis B related liver fibrosis with a fractional order calculus diffusion model
Ruofan Sheng1, Yunfei Zhang2, Mengsu Zeng1, and Yongming Dai2
1Zhongshan Hospital affiliated to Fudan University, Shanghai, China, 2Central Research Institute, United Imaging Healthcare, Shanghai, China
FROC-DWI is valuable for liver fibrosis staging, and the combination of FROC-derived parameters may serve as a promising and reliable tool for noninvasive staging of liver fibrosis.
Fig. 1 FROC-derived parametric maps of one patient with low stage (F0) of liver fibrosis.
Fig. 5 Receiver operating characteristic curves for prediction of liver fibrosis (A) stage 1 or greater, (B) stage 2 or greater, (C) stage 3 or greater and (D) stage 4 using the combined diffusion index (D, β, μ and ADC), APRI, and FIB-4. Numbers are areas under the curves with 95% confidence intervals in parentheses.