Impact of motion on simultaneously acquired PET/MRI of myocardial infarcted heart.
Heeseung Lim1, Benjamin Wilk 1,2, Jane Sykes 1, John Butler 1, Gerald Moran3, Jonathan Thiessen1,2, Gerald Wisenberg1,4, and Frank S Prato1,2
1Lawson Health Research Institute, London, ON, Canada, 2Medical Biophysics, Western University, London, ON, Canada, 3Siemens Healthcare Limited, Oakville, ON, Canada, 4MyHealth Centre, Arva, ON, Canada
This
study investigates the impact of motion in simultaneously acquired myocardial
PET/MRI data and finds a significant discrepancy in functional data between
registered to post-mortem images to non-registered images.
Comparison of net influx rate (Ki)
between original dynamic PET data and transformed dynamic PET data. Heart
polar-map comparison is shown in a) & b). Correlation scatter plot shows
significant correlation with correlation coefficient =
0.959 in c).
Comparison
of net influx rate (Ki) between original and transformed
images at 4 different segments (left anterior descending artery, left
circumflex artery, right coronary artery, apex) of heart and 3 different time
points (before the lipid infusion, during the lipid infusion and after the
lipid infusion).