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Photoperiodic Regulation of hypothalamic metabolism : a preliminary single voxel Magnetic Resonance Spectroscopy investigation at 3T
Nathalie Just1, Pierre-Marie Chevillard1, and Martine Migaud1
1NhyRVana, INRAE, Nouzilly, France
Photoperiodism regulated the metabolism of the female sheep hypothalamus as demontrated by significant changes of Glu, Gln and NAA during short days compared to long days. The sheep brain is an interesting model to explore hypothalamic mechanisms of metabolic regulation.
Comparison of Neurochemical profiles (µmol/g) acquired within the hypothalamus of sheep at 4 time points (P01, P02, P03 and P04) during long days (Long period, LP) and at 4 time points during short days (Short period, SP). * p< 0.05; ** p<= 0.01

A. Neurochemical profiles (µmol/g) during Long days (LP) at 4 time points. * p<0.05

B. Neurochemical Profile (µmol/g) during Short days (SP) at 4 time points. * p<0.05 Gln and Glu concentrations at P01 were significantly different compared to concentrations at later time points