Rajakumar Nagarajan1, Anant Shinde2,3, Muhammed Enes Gunduz2,3, and Gottfried Schlaug2,3
1Human Magnetic Resonance Center, Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, United States, 2Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA, United States, 3Baystate Medical Center, University of Massachusetts Medical School, Springfield, MA, United States
1Human Magnetic Resonance Center, Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, United States, 2Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA, United States, 3Baystate Medical Center, University of Massachusetts Medical School, Springfield, MA, United States
We studied the effects of motor region tDCS on
metabolite levels in a spectroscopic voxel with repeated 5min of constant
current dose. This
study provides insights into how tDCS leads to polarity dependent modulation of
metabolites and might provide a model for future MRS stimulation studies.
Figure 1.
Experimental setup: a) electrode placement and stimulator modes; b)
setup for applying tDCS inside the MR scanner; and c) 45 minutes of tDCS-MRS
scanning protocol timing diagram
Figure 3.
Short term and Cumulative effect of GABA and Glx with respect to
Creatine changes of Anode and Cathode