Julia E. Kline1, Weihong Yuan1, Karen Harpster1, and Nehal A. Parikh1
1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States
1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States
Very preterm infants are at high risk for motor impairments, such as cerebral palsy. Graph theory metrics from term diffusion MRI connectomes and cortical surface area and subcortical volumes derived from term structural MRI are associated with the early diagnosis of cerebral palsy.
Figure 3: Subcortical and cortical volumes (top) and cortical surface area (bottom) for regions that were negatively associated with early diagnosis of cerebral palsy are shown in blue (shade is arbitrary). Grey/white regions are not significant.
Figure 1: Alignment (3rd column) of the 90-region Automated Anatomical Labeling atlas (2nd column) with diffusion space tractography (1st column) for an example subject. From here, we calculate the mean fractional anisotropy for all streamlines connecting each regional pair as a 90x90 symmetrical matrix.
