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Estimation of Glomerular Filtration Rate in a Pediatric Population using Renal Phase Contrast MRI
Alex J Barker1, Lorna P Browne1, Michal Schafer2, Erin K Englund2, Takashi Fujiwara2, Kristen J Nadeau2, and Petter Bjornstad2
1Radiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States, 2University of Colorado, Anschutz Medical Campus, Aurora, CO, United States
The correlation between gold-standard GFR by 125I iothalamate clearance and renal blood flow measurements from a noninvasive 20-minute PC-MRI are superior to that of the commonly used endogenous filtration markers, serum creatinine or cystatin C.
Figure 1: Study protocol, MRI planning, and quantitative flow measurements obtained with PC-MRI (note: renal veins not shown).
Figure 2: Scatter plots of: (a) total left and right arterial renal blood flow, and (b) the average left and right peak renal blood flow.