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Feasibility of quantitative T2 mapping imaging in the diagnosis and chemotherapy response tracking of rectal cancer
Yunxing Tang1, Ailian Liu1, Jiazheng Wang2, Zhiwei Shen2, Yunsong Liu1, Yuhui Liu1, Anliang Chen1, and QingWei Song1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China
T2 values were significantly higher in rectal cancer than those in the healthy rectal wall, and significantly increased after chemotherapy. Quantitative T2 mapping might be a promising non-invasive method in the diagnosis and chemotherapy response tracking of rectal cancer.
Table 3. Comparison of T2 values in rectal cancer and healthy rectal wall(A); Comparison of T2 values in rectal cancer before and after chemotherapy(B)
Figure 2. The AUC of T2 mapping values to distinguish rectal cancer before and after chemotherapy was 0.774 with sensitivity of 0.588 and specificity of 0.900 and the feasible threshold was 81.738 (A). The AUC of T2 mapping values to distinguish normal rectal wall and rectal cancer was 1 with sensitivity of 0.971 and specificity of 0.929 and the feasible threshold was 66.183 (B).