Martin Buechert1 and Arnd-Oliver Schäfer2
1Medizinische Fakultät, Universität Freiburg, Freiburg, Deutschland, Radiologische Klinik, Medizinphysik, Universitätsklinikum Freiburg, Freiburg, Germany, 2Klinik für Radiologie, Klinikum St. Georg Leipzig, Leipzig, Germany
1Medizinische Fakultät, Universität Freiburg, Freiburg, Deutschland, Radiologische Klinik, Medizinphysik, Universitätsklinikum Freiburg, Freiburg, Germany, 2Klinik für Radiologie, Klinikum St. Georg Leipzig, Leipzig, Germany
Significant changes of tumor properties during and after neoadjuvant
radiochemo therapy are observed in DCE- as well as in DWI-MRI applied before,
48hours, 2, 4 and 12 weeks after treatment start in 55 patients with locally advanced
rectal cancer.
Fig. 2 Percentage change of ADC over time for the 4 patient groups. Patients with
no or minimal regression (class 1-3) show an strong increase in ADC over the
time, while patients with strong regression (class4) only showed a minimal
increase followed by a slight decrease of ADC over time.
Fig. 1 T1- (left),
T2-weighted (center) and ADC (right) image of patient with advanced rectum
carcinoma.