Romtheera Kamronritthisorn1, Kritdipha Ningunha2, Peeratat Suppapanya1, Sunee Bovonsunthonchai3, Doonyaporn Wongsawaeng 1, Yudthaphon Vichianin4, Theerapol Witthiwej5, Weerasak Muangpaisan6, Panida Charnchaowanish1, Siriwan Piyapittayanan1, Orasa Chawalparit1, and Chanon Ngamsombat1
1Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Department of TELE-Radiology, Bangkok Hospital Headquarters, Bangkok, Thailand, 3Faculty of Physical Therapy, Mahidol University, Bangkok, Thailand, 4Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand, 5Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 6Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
1Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Department of TELE-Radiology, Bangkok Hospital Headquarters, Bangkok, Thailand, 3Faculty of Physical Therapy, Mahidol University, Bangkok, Thailand, 4Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand, 5Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 6Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
A significant reduction of ventricular volume after shunt surgery in idiopathic normal pressure hydrocephalus patients is found among long term shunt responders andhas a negative correlation with improved cognitive clinical scores.
Figure 3. Axial T1W images (top row) and segmented brain using freesurfer (bottom row) used for ventricular volume evaluation in iNPH patient
Figure 2. Correlation analysis between a reduction in ventricular volume and changes in iNPHGS scores in cognitive domain showing a moderate degree of a significant negative correlation (r = -0.408, p = 0.023).
