2385
Feasibility of water peak MRS without water suppression for the evaluation of cerebrospinal fluid
Toshiaki Taoka1,2, Rintaro Ito1,2, Rei Nakamichi2, Takashi Abe2, Toshiki Nakane2, Hisashi Kawai2, Mayuko Sakai3, and Shinji Naganawa2
1Department of Innovative Biomedical Visualization (iBMV), Nagoya University, Nagoya, Japan, 2Radiology, Nagoya University, Nagoya, Japan, 3Canon Medical Systems Corporation, Otawara, Japan
Water peaks in MRS changed with the solute concentrations of NaCl, Glu, and Alb. Differences in water peaks were observed among the CSF phantom simulating normal, bacterial meningitis, and obstruction of the subarachnoid space samples.

Figure 5

Compared to artificial CSF simulating normal CSF, artificial CSF simulating bacterial meningitis and artificial CSF simulating obstruction of the subarachnoid space showed higher peaks and lower signal values at the side slope of the peak.

Figure 4

The peak heights/FWHMs of each albumin concentration were as follows: 2 mmol/L: 4.73×1011/0.016 ppm, 0.2 mmol/L: 2.08×1011/0.080 ppm, 0.02 mmol/L: 8.71×1011/0.016 ppm, 0.01 mmol/L: 9.75×1011/0.020 ppm, and 0.005 mmol/L: 9.45×1011/0.020 ppm.