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Evaluation of different b-value sampling strategies in cerebral IVIM: application to interstitial fluid
Gerhard Drenthen1, Jacobus Jansen1, Paulien Voorter1, Joost de Jong1, and Walter Backes1
1Maastricht University Medical Center, Maastricht, Netherlands
When a large intermediate diffusion component is present in the IVIM signal (eg. white matter hyperintensities), b-value sampling strategies specifically aimed to quantify this component can provide better estimates of $$$f_{int}$$$ compared to linear or logarithmic spaced b-values.
Figure 1: The nine different sets of b-values used to estimate the intermediate fraction. Red: logarithmically scaled, green: linearly scaled, and blue: oversampled $$$b \cdot D_{int}$$$ range.
Figure 3: Precision and accuracy for the $$$f_{int}$$$ estimation in white matter hyper-intensities. The arrows show the effect of acquiring more b-values for logarithmically scaled (red) linearly scaled (green), and over-sampling $$$b \cdot D_{int}$$$ range (blue) b-value strategies.