Arun Venkataraman1, Benjamin Risk2, Deqian Qiu3,4, Jianhui Zhong1,5, and Zhengwu Zhang6
1Physics and Astronomy, University of Rochester, Rochester, NY, United States, 2Biostatistics and Bioinformatics, Emory University, Atlanta, GA, United States, 3Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, 4Biomedical Engineering, Emory University, Atlanta, GA, United States, 5Imaging Sciences, University of Rochester Medical Center, Rochester, NY, United States, 6Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, United States
1Physics and Astronomy, University of Rochester, Rochester, NY, United States, 2Biostatistics and Bioinformatics, Emory University, Atlanta, GA, United States, 3Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, 4Biomedical Engineering, Emory University, Atlanta, GA, United States, 5Imaging Sciences, University of Rochester Medical Center, Rochester, NY, United States, 6Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, United States
In this study, we found that slice and phase acceleration lead to increased noise amplification. This leads to worse DTI fitting and instability of tractography that is preferentially seen in the frontal areas, with relative sparing of the occipital areas.
Figure 2 g-factor calculated for all accelerated acquisitions, red line indicates g-factor of 1, which represents the SNR of the unaccelerated (S1P1) dMRI acquisiton. p-values indicated by asterisks and were calculated using a paired t-test, in this figure, all p < 0.0001 (****).
