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Evaluation of renal oxygenation and hemodynamics in patients with chronic kidney disease by BOLD-MRI and intrarenal Doppler ultrasonography
Jing Yang 1, Shuohui Yang 2, Zheng He3, Mengxiao Liu4, and Caixia Fu5
1Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 2Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 3Ultrasonography, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 4MR Scientific Marketing, Siemens Healthcare, Shanghai, China, 5MR Applications Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China
BOLD-MRI and IDU evaluating renal oxygenation and hemodynamics on CKD
Fig.1 Five typical T2* images of BOLD-MRI in healthy volunteer and CKD1-4 patients. a Healthy volunteer, male/26 years old. b Stage 1 CKD patient, female/28 years old. c Stage 2 CKD patient, male/29 years old. d Stage 3 CKD patient, female/ 62 years old. e Stage 4 CKD patient, female/58 years old.
Fig.2 Correlation coefficients among the cortical T2* (COT2*), outer medullary T2* (OMT2*) values, peak systolic velocity (PSV), and estimated glomerular filtration rate (eGFR). a Correlation of COT2* values and eGFR. b Correlation of OMT2* values and eGFR. c Correlation of PSV values and eGFR. d Correlation of COT2* values and PSV values. e Correlation of OMT2* values and PSV. Spearman coefficient testing was performed to assess statistical significance.