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The value of DKI in assessing the pathologic microstructural changes in the early stages of renal cold ischemia-reperfusion injuries
Yizhong Yuan1, Jipan Xu1, Yan Ren2, Lihua Chen2, Jinxia Zhu3, Robert Grimm4, and Wen Shen2
1First Central Hospital Institute, Tianjin Medical University, Tianjin, China, 2Department of Radiology, Tianjin First Center Hospital, Tianjin, China, 3MR Collaboration, Siemens Healthcare, Beijing, China, 4MR Application development, Siemens Healthcare GmbH, Erlangen, Germany
The values of diffusion kurtosis imaging can effectively and non-invasively assess the microstructural changes of renal CIRIs in the early stages. The MK values may reflect more detailed microstructural changes compared with the MD values.
Figure 1. Various b- value images in a normal rat. b = 0, 500, 1000, 1500, and 2000 s/mm2 separately from left to right.
Figure 2. The MK values of the cortex (a), medulla (b), and MD values of the cortex (c), medulla (d) in different groups.