Xinxin Zhang1 and Yan Chen1
1Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital，Chinese Academy of Medical Sciences and Peking Union Medical College, BeiJing, China
1Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital，Chinese Academy of Medical Sciences and Peking Union Medical College, BeiJing, China
The baseline ADC value before treatment could
not predict tumor response to NAC in patients with MIBC. After NAC treatment, the
ADC value of responders increased significantly.
Table 1
Mean Values of pre- and post-NAC, and percentage
increases in ADC, Between Responders and Non-responders
Figure 1: Images obtained in a 69-year-old man with muscular invasive bladder
cancer who was a responder (pT2N0M0). (a, d) pre-NAC (a) and post-NAC (d) Axial
T2 weighted image. (b, e) pre-NAC (b) and post-NAC (e) DWI Imaging (b=1000 s/mm2).
In b, maximal diameter of the hyperintense signal mass was 2.6 cm. In e, tumor
regressed with a maximum diameter of 0.6cm. The tumor diameter was reduced by 77%.
(c, f) pre-NAC (c) and post-NAC (f) ADC maps. In c, the mass mean ADC was 1.21×10 -3 mm2/s. In f, NAC increased the mean ADC of this lesion to 2.11×10 -3 mm2/s.
