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Brain aging in cynomolgus macaques and common marmosets explored by mapping the magnetic susceptibility and R2*
Rakshit Dadarwal1,2, Judith Mylius1, and Susann Boretius1,2,3
1Functional Imaging Laboratory, German Primate Center, Göttingen, Germany, 2Georg August Universität Göttingen, Göttingen, Germany, 3Leibniz Science Campus Primate Cognition, Göttingen, Germany

In this work we demonstrate the potential of QSM and R2* to characterize healthy brain aging in macaques and marmosets.

Figure 1. QSM group average of young (7-8 years) and old (15-20 years) macaque brains. Arrows point out substructures of the basal ganglia such as putamen and globus pallidus. An increase in the magnetic susceptibility of deep gray matter nuclei can be observed with age.
Figure 2. Group average of QSM and R2* map for the 4 marmoset age groups. A prominent increase in QSM and R2* contrast can be seen with increasing age particularly for deep grey matter nuclei. Arrows indicate substructures of the globus pallidus.