Lei Wei1, Ming Ding1, Xiao Xiao1, and He Wang1,2
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, shanghai, China, 2Human Phenome Institute, Fudan University, Shanghai, China, Shanghai, China
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, shanghai, China, 2Human Phenome Institute, Fudan University, Shanghai, China, Shanghai, China
We combine the ultra-high field magnetic imaging and cell imaging technique to verify the importance of some brain region in non-human chronic pain model.
Group comparison between CCI rat and healthy controls. The insula and nucleus accumbens showed significantly increased Alff in the CCI group (red area). The Alff was found significantly reduced in the motor cortex (blue area).
Immunohistochemical map of CCI rat. The dotted-line box and white arrows indicate the expression level of the p-Erk increase significantly in insula, S1 and NAc.