Alicia Cronin1,2, Patrick Liebig3, Sarah Detombe4, Neil Duggal4, and Robert Bartha1,2
1Medical Biophysics, University of Western Ontario, London, ON, Canada, 2Centre for Functional and Metabolic Mapping, Robarts Research Institute, London, ON, Canada, 3Siemens Healthineers, Erlangen, Germany, 4Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, ON, Canada
1Medical Biophysics, University of Western Ontario, London, ON, Canada, 2Centre for Functional and Metabolic Mapping, Robarts Research Institute, London, ON, Canada, 3Siemens Healthineers, Erlangen, Germany, 4Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, ON, Canada
A prototype 2D gradient echo CEST
sequence utilizing a gradient-echo readout with centric reordering on a
Siemens scanner was utilized in conjunction with a respiratory correction
method to improve amide proton CEST contrast at 3.0 T in the spinal cord.
Figure 2:
Demonstration of
the respiratory correction in a full CEST spectrum collected in the spinal cord
with no correction (blue) and implemented correction (orange) demonstrated.
Figure 1:
A: Raw sagittal spinal cord CEST image.
B: CEST spectrum of spinal cord with the interleaved non-saturated scans demonstrating the global respiratory effect.
