2617
High Efficient Reconstruction Method for IVIM Imaging Based on Deep Neural Network and Synthetic Training Data and its Application in  IVIM-DKI
Lu Wang1, Zhen Xing2, Jian Wu1, Qinqin Yang1, Congbo Cai1, Shuhui Cai 1, Zhong Chen1, and Dairong Cao2
1Department of Electronic Science, Xiamen University, Xiamen, Fujian, China, 2Department of Radiology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
We proposed a deep neural network-based reconstruction method with synthetic training data for IVIM imaging and extend it to hybrid IVIM-DKI (diffusion kurtosis imaging) model fitting. Experimental results show that our method owns prominent performance with a remarkably short  time.
Figure 2. Reconstructed parametric maps (D, f and D*) of IVIM model using proposed method, least square and Bayesian algorithm. (a) A 59-year-old man with pathologically confirmed oligodendroglioma. The lesion hardly enhanced on postcontrast T1 weighted image. (b) A 57-year-old man with pathologically confirmed IDH wild-type astrocytoma. The lesion shows remarkable enhancement on postcontrast T1 weighted image. (c) A 49-year-old man with pathologically confirmed IDH-mutated astrocytoma. The lesion hardly enhanced on postcontrast T1 weighted image.
Figure 4. RMSE of the estimated IVIM parameters (D, f and D*) for proposed method, least square (LS), and Bayesian algorithm (BP) under SNR from 10 to 80 dB.