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Improved resting-state fMRI with through-plane phase precompensated spectral-spatial pulses
Christopher Sica1, Hairong Chen2, Guangwei Du2, Sangam Kanekar1, Jianli Wang1, Qing X Yang3, and Prasanna Karunanayaka1
1Radiology, Penn State College of Medicine, Hershey, PA, United States, 2Neurology, Penn State College of Medicine, Hershey, PA, United States, 3Neurosurgery, Penn State College of Medicine, Hershey, PA, United States
fMRI scans with long echo times are vulnerable to signal loss due to through-plane dephasing caused by susceptibility field gradients. This work evaluates the ability of phase-precompensated spectral-spatial RF pulses to improve detection of resting state fMRI activity in these regions.
Single-subject ALFF & ReHo maps, acquired from the same subject depicted in Fig. 1. White arrows highlight a region of strong recovery and a node that was recovered with the SPSP pulse.
Regions of significant difference (p < 0.05) between the compensated & uncompensated ALFF & ReHo maps, calculated across all subjects.