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Development of an optimized approach to spinal cord fMRI based on the combination of an ad hoc acquisition method and data analysis pipeline
Michela Fratini1, Marta Moraschi2, Laura Maugeri1, Silvia Tommasin3, Mauro DiNuzzo2, Julien Cohen-Adad4, Fabio Mangini5, Daniele Mascali6, and Federico Giove2
1CNR-Nanotec, rome, Italy, 2Centro Ricerche Enrico Fermi, Rome, Italy, 3Sapienza University of Rome, Rome, Italy, 4Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada, 5Santa Lucia Foundation, Rome, Italy, 6Centro Ricerche Enrico Fermi, rome, Italy

We investigated the impact of the acquisition direction strategy on the quality of pre-processed images  and activation analysis. To this purpose, several benchmarks such as sensitivity and reproducibility have been computed and used to test the differences between axial and sagittal plane.

Maps of the mean sensitivity, across subjects, for images acquired along axial and sagittal directions planes. CNR is comparable for the two protocols
Reproducibility in gray matter (on the left panel) and in Cord (in the right panel). Reproducibility is greater for axial acquisition protocol than sagittal one scanning.