Alexander JS Beckett1,2, Salvatore Torrisi1,2, Kawin Setsompop3, David A Feinberg1,2, and An T Vu4,5
1Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States, 2Advanced MRI Technologies, Sebastopol, CA, United States, 3Radiological Sciences Laboratory, Stanford University, Stanford, CA, United States, 4Radiology, University of California, San Francisco, CA, United States, 5San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States
1Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States, 2Advanced MRI Technologies, Sebastopol, CA, United States, 3Radiological Sciences Laboratory, Stanford University, Stanford, CA, United States, 4Radiology, University of California, San Francisco, CA, United States, 5San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States
We demonstrate the use of generalized Slice Dithered Enhanced Resolution (gSLIDER) for high-resolution spin-echo (SE) fMRI. Activations were comparable to standard SE fMRI at varying levels of regularization, demonstrating the suitability of this method for high-resolution fMRI.
Figure 2 – Activation maps for 1mm Spin Echo (SE) and gSlider Super Resolution (SR) data with different levels of regularization (Lambda).
5×-gSlider with ‘slice-phase dither’ encoding to provide highly independent basis, while maintaining high image-SNR in each individual slab acquisition. The DIST RF pulses are shown in the left column, with real and imaginary parts shown in black and green respectively. The corresponding slab profiles are shown in the middle column, each with a π phase dithering applied to a different sub-slice.