2732
Reproducibility and repeatability of quantitative pCASL measurements in a 3D-printed perfusion phantom
Yiming Wang1, Limin Zhou1, Durga Udayakumar1,2, and Ananth J. Madhuranthakam1,2
1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States
We assessed the reproducibility and repeatability of perfusion measurements using multi-PLD 2D pCASL over 5 weeks with a 3D-printed perfusion phantom. Intra-class correlation coefficients of measured perfusion and T1 are 0.96 and 0.94, indicating good reproducibility and repeatability.
Figure 3. Signal intensities (open circle) and their regression analysis results (solid line) over 20 PLDs are shown for 3 runs of 2D pCASL in one session (a), and for all 5 sessions across 5 weeks (b). Curves were shifted horizontally slightly so that they all peak at LD+PLD = 5000 ms.
Figure 2. perfusion difference images of 20 PLDs ranging from 0.2 s to 7.8 s from 3 runs (a, b and c) of 2D pCASL sequences in one session, compared against images from one run (d) of another session showing similar signal intensities.