2735
Intrasession reliability of arterial spin labeled MRI measured perfusion in GBM at 3T
Limin Zhou1, Yiming Wang1, Marco Da Cunha Pinho1,2, Edward Pan3,4,5, Yin Xi1,6, Joseph A Maldjian1,2, and Ananth J Madhuranthakam1,2
1Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 3Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, DALLAS, TX, United States, 4Department of Neurological Surgery, University of Texas Southwestern Medical Center, DALLAS, TX, United States, 5Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, DALLAS, TX, United States, 6Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States
In this study, we compared the 3D TSE-CASPR measured perfusion with clinically available 3D GraSE in GBM patients at 3T. The results showed that 3D pCASL with TSE-CASPR is more robust to B0 inhomogeneities and has higher intrasession reliability than the clinical sequence, 3D pCASL with GraSE.
Figure 1. Two runs of 3D pCASL with TSE-CASPR and three dynamics of 3D pCASL with GraSE in a 26-year old healthy volunteers (a) and a 71-year old GBM patient (b).
Table 1. Intraclass correlation coefficient (ICC) and its 95% confidence interval (CI) for 2 runs of 3D pCASL with TSE-CASPR and 3 dynamics of 3D pCASL with GraSE.