Jörn Huber1, Daniel Hoinkiss1, and Matthias Günther1,2
1Fraunhofer MEVIS, Bremen, Germany, 2University of Bremen, Bremen, Germany
1Fraunhofer MEVIS, Bremen, Germany, 2University of Bremen, Bremen, Germany
Arterial Spin Labeling (ASL) allows non-invasive assessment of liver perfusion. However, breathing motion, low perfusion rates and off-resonance are challenges in liver ASL. In this work, a robust implementation for a pulsed ASL sequence using 3D GRASE is given, addressing these challenges.
Figure 5: Perfusion weighted images using background suppression with two inversion pulses and the proposed multi-breathhold acquisition scheme and a free-breathing acquisition respectively. Arrows indicate areas with subtraction errors under free-breathing which are likely misinterpreted as perfusion signal.
Figure 3: Three exemplary slices of perfusion-weighted images using two inversion pulses and different inflow times TI.