2741
ASL perfusion and disability in primary progressive MS: an observational cohort study
Clara Delacour1, Ahmed-Ali El Ahmadi1, Gilles Brun1, Nadine Girard1,2, Christoph Heesen3,4, Arzu Ceylan Has3,4, and Jan-Patrick Stellmann2,3,4,5
1Neuroradiology, APHM La Timone, Marseille, France, 2Aix-Marseille Univ, CNRS, CRMBM, UMR 7339, Marseille, France, 3Institute of Neuroimmunology and MS (INIMS), University Medical Centre Hamburg-Eppendorf, Hamburg-Eppendorf, Germany, 4Neurology, University medical centre Hamburg-Eppendorf, Hamburg-Eppendorf, Germany, 5APHM La Timone, CEMEREM, Marseille, France

We notice no relevant change of brain perfusion over up to five years in primary progressive MS population cohort (77 patients). An association between higher regional perfusion rates and cognitive performance and hand functioning has been highlighted. 

Figure 1