Chenyang Zhao1, Ze Wang2, and Danny Wang1
1Laboratory of Functional MRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States, 2Department of Diagnostic Radiology and Nuclear Medicine, School of Medicine, University of Maryland, Baltimore, MD, United States
1Laboratory of Functional MRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States, 2Department of Diagnostic Radiology and Nuclear Medicine, School of Medicine, University of Maryland, Baltimore, MD, United States
This work
presented a digital brain perfusion phantom with flexible parameter settings to
achieve various ASL configurations. It provides a reliable reference to
validate ASL post-processing software.
(a) A Sample slice for T1 weighted MPRAGE,
Label, Control, and M0 image. (b) A sample slice for 5-PLD ASL images. The PLD
ranges from 500 to 2500 ms with an interval of 500 ms. (c) The perfusion map of
the checkerboard phantom at PLD = 1000 that is embedded in a lower slice of the
phantom. (d) The simulated perfusion signal of GM and WM using a 5-delay 3D
pCASL protocol.
Resulted CBF (ml/100g/min) and ATT (ms) maps of
the digital realistic phantom from 4 different ASL data processing software, including
BASIL, Cereflow, MRI Cloud, and ASLtbx, under a normal SNR condition and a low
SNR condition.
