2752
Prostate Perfusion Mapping using Fourier-Transform based Velocity-Selective Pulse Trains:  Choice of Cutoff Velocity and Comparison with Brain
Dapeng Liu1,2, Dan Zhu3, Wenbo Li1,2, and Qin Qin1,2
1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 3Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States
Prostate blood flow and blood volume mapping using VSASL prepared by Fourier-transform based velocity-selective pulse trains were compared among different cutoff velocities (Vc). The results suggest that lower Vc of VSASL is demanded for prostate than for brain.
Figure 2: Brain (a) and prostate (b) PWS and corresponding tSNR maps from one representative subject with four out of all ten slices. Both blood flow (CBF for brain and PBF for prostate) and blood volume (CBV for brain and PBV for prostate) maps were shown. M0 and DIR images were also shown above. Note that in the CBV PWS and tSNR images, the CSF in leteral ventricles display dark as it has negative signal due to a combination of long T2 values of CSF and the higher B1+ scale at the center of the brain.
Figure 4: Averaged blood flow PWS (a) and its tSNR (b), blood volume PWS (c) and its tSNR (d), in ROIs of GM, WM and prostate from four subjects.