Figure 3 Selective clinical MP-RAGE (first column), T2-FLAIR (second column) and STAIR-dUTE (last three columns) images of two representative patients with MS (first row: a 49-year-old female; second row: a 69-year-old female). MS lesions appeared hypointense on the MP-RAGE image and hyperintense on the T2-FLAIR image as indicated by the yellow arrows. These lesions also show signal loss on the magnitude images in the first echo images (third column), magnitude echo subtracted images (fourth column) and complex echo subtracted images (last column) using the STAIR-dUTE sequence.

Figure 2 A volunteer study showing the generation of ultrashort T2 signals with the methods used in this study. The first row shows magnitude images for the first echo (A) and the second echo (B), as well as the corresponding phase images for the first echo (C) and second echo (D). Panel E shows the ΔB0 field map used for the complex ES. Magnitude of the first echo (F), magnitude echo subtracted (G), and complex echo subtracted (H) images obtained with the STAIR-dUTE sequence are shown. The magnitude of the first echo image (A) is displayed again in (F) for closer comparison with (G) and (H).