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Deep Cartilage UTE-T2* Shows Compositional Heterogeneity in Patients with Degenerative Meniscus Tears
Ashley A. Williams1,2, Karyn E. Chappell1,2, and Constance R. Chu1,2
1Orthopaedic Surgery, Stanford University, Stanford, CA, United States, 2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, United States
Meniscus and cartilage UTE-T2* was compared to arthroscopy in degenerative meniscus tear patients.  Elevated UTE-T2* was observed in degenerate menisci. However, increasing intra-operative cartilage grade was not associated with strictly increasing cartilage UTE-T2*.
Figure 2. Sample UTE-T2* maps. Top row: a 39-yr male DMT patient with a complex tear to the posterior horn of his medial meniscus (a) and arthroscopically detected intact-but-softened medial and lateral femoral condylar cartilage but partial to full-thickness disruptions of his tibial cartilages (a,b). Bottom row: an uninjured, healthy 24-yr male with homogeneously low UTE-T2* in both medial and lateral menisci and smoothly laminar UTE-T2* distributions in his articular cartilage (c,d).
Figure 1. Softened but intact cartilage regions (scope grade 1) tend to have elevated deep cartilage UTE-T2* values compared to uninjured controls (yellow bars, a,b,c), while cartilage regions with disrupted articular surfaces tend to show UTE-T2* values consistent with or lower than uninjured controls (red bars, a-d). ANOVA (or Kruskal-Wallis) found no significant differences between groups suggesting a high degree of variability in deep cartilage UTE-T2* values of DMT patients with both intact and disrupted articular surfaces. Error bars represent ± standard error of the mean.