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Automated Pipeline for Quantitative MRI Evaluation of Knee Articular Cartilage in Longitudinal Osteoarthritis Trials
Vladimir Juras1, Veronika Janáčová1, Pavol Szomolanyi1, Markus Schreiner2, Didier Laurent3, Celeste Scotti3, and Siegfried Trattnig1
1Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, 2Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria, 3Novartis Institutes for Biomedical Research, Basel, Switzerland
Fully automated analysis of knee articular cartilage combines quantitative morphological and compositional information from 21 anatomically well-defined subfields of the knee joint and provides reproducible and robust evaluation of the cartilage volume, thickness and composition. 
A diagram of fully automated proton MRI evaluation
A diagram of fully automated sodium MRI evaluation