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Evidence on the association between executive functions and tractography-derived nodal properties in Parkinson's disease

Giacomo Tomezzoli^1,2, Lisa Novello², Francesca Saviola², Stefano Tambalo², Beatrice Federica Luciani², Enrica Pierotti², Céline Charroud ², Alessandro Gober², Francesca Giacomoni², Pamela Narduzzi², Claudia Meli², Marika Falla², Alessandra Dodich², Luca Turella², Costanza Papagno², and Jorge Jovicich²
¹DiPSCo, Department of Psychology and Cognitive Science, University of Trento, Rovereto, Italy, ²CIMeC, Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy

We provide initial evidence for associations between brain tractography-derived nodal properties and executive functions performance assessment in brain executive regions in a group of Parkinson’s patients.

Figure 5: Betweenness Centrality and nodal Clustering Coefficient positive correlations (red nodes) and negative correlations (blue nodes) with EFs scores in nodes enrolled in the analysis. SFG: superior-frontal-gyrus; IPG: inferior-supramarginal-parietal-gyrus.

Figure 3: Topological distribution of node degree (k); the size of each node represents k. SFG: superior-frontal-gyrus; OG: orbital-gyrus; SPG: superior-parietal-gyrus; IPG: inferior-supramarginal-parietal-gyrus