Simultaneous Mapping of Myelin Water Fraction and Quantitative Susceptibility of Whole Brain
Quan Chen1, Huajun She1, Ming Zhang1, Hongjiang Wei 1, and Yiping P. Du1
1Shanghai Jiao Tong University, Shanghai, China
The feasibility of simultaneous MWF/QSM mapping is demonstrated
by using the multi-echo gradient echo (mGRE) sequence in this study.
The retrospective and the perspective undersampling experiments have shown the
potential of obtaining whole brain QSM/MWF
quantifications in 1 minute.
Figure
4. The MWF/QSM maps of 8
adjacent slices from one prospectively undersampled datasets with R=6 and the
fully-sampled dataset.
Figure 3. The profile plots corresponding to the black lines in
the QSM maps of the fully-sampled data and the TDLLS reconstructed data from 9
subjects (R=6). The blue lines and green lines in the plots refer to the signal
variations of the fully-sampled data and the TDLLS reconstructed data,
respectively. High agreements are observed
between the signal of TDLLS reconstructed data and that of the fully-sampled
data.