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Diffusion sensitivity of spin echo sequences affects white matter R2 fiber orientation dependency
Christoph Birkl1, Christian Kremser2, Alexander Rauscher3, and Elke Ruth Gizewski1
1Department of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria, 2Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria, 3UBC MRI research Centre, University of British Columbia, Vancouver, BC, Canada
The different diffusion sensitivity of spin echo and turbo spin echo sequences affects the estimation of white matter R2 fiber orientation dependency.
Figure 3: R2, normalized to average global white matter R2, as a function of white matter fiber orientation. R2 was acquired using multiple single echo spin echo (SE) sequences (violet curve), a multi-echo SE sequence (green curve), multiple single echo turbo spin echo (TSE) sequences (blue curve) and a dual-echo TSE sequence (orange curve).
Figure 1: R2 maps of a volunteer acquired using multiple single echo spin echo (SE) sequences (a), a multi-echo SE sequence (b), multiple single echo turbo spin echo (TSE) sequences (c) and a dual-echo TSE sequence (d).