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A comparative study of R2*, UTE-T2* and T1rho mapping for evaluation of degenerative alterations in human intervertebral discs
LiLan Wu1, JianJun Zhou2, and Pu-Yeh Wu3
1Department of Radiology, Fudan University Affiliated Zhongshan Hospital Xiamen Branch, Xiamen, China, 2Department of Radiology, Fudan University Affiliated Zhongshan Hospital, Shanghai, China, 3GE Healthcare, Beijing, China
The current study demonstrated the feasibility of quantitative evaluation of human IDD in vivo by R2*, UTE-T2* and T1rho mapping. We found that T1rho value is superior to UTE-T2* and R2* values for differential diagnosis of the early IVD, while UTE-T2* value is optimal for differential diagnosis of advanced IVD. T1rho mapping can be considered an effective tool for distinguishing IDD at the earlier stage of the degenerative process.  
Fig.1MR images of the lumbar spine .Every IVD was cut into 5 uniform parts in each UTE,R2*and T1rho.
Fig.2 Post hoc multiple comparisons among three Disc degeneration groups