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Evaluation of Lumbar Disc Degeneration Using Ultrashort Echo Time Magnetization Transfer (UTE-MT) Imaging in Cartilaginous Endplate
Jin Liu1, Yajun Ma2, Jianwei Liao1, Xiaojun Chen1, Wei Li1, Lin Yao1, Zhihai Su3, Long Qian4, Jiang Du2, and Shaolin Li1
1Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China, 2Department of Radiology, University of California, San Diego, CA, United States, 3Department of Orthopedics, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China, 4MR Research, GE Healthcare, Guangzhou, China
Our findings suggest that deficits in CEP composition, as indicated by high UTE-MTR, associate with more severe disc degeneration in patients. It is supposed that UTE-MTR of cartilaginous endplate may be a useful biomarker to predict early disc degeneration.
Figure 1: UTE-MT imaging in lumbar of a 67‐year‐old male volunteer. Figure A: UTE-MT-ON; Figure B: UTE-MT-OFF; Figure C: UTE-MTR map
Figure 2: Correlation between cartilaginous endplate UTE-MTR and Pfirrmann grade of disc in 62 subjects. Cartilaginous endplate UTE-MTR showed a positive correlation with Pfirrmann grade of disc.